| Paper ID | A-3-3.3 |
| Paper Title |
Quantification Analysis of Behavioral Changes after Sciatic Nerve Ligation in Rats |
| Authors |
Panyawut Sri-iesaranusorn, Nara Institute of Science and Technology, Japan; Saeka Shimochi, University of Turku, Finland; Naoki Ono, Nara Institute of Science and Technology, Japan; Emrah Yatkin, Hidehiro Iida, University of Turku, Finland; Kazushi Ikeda, Junichiro Yoshimoto, Nara Institute of Science and Technology, Japan |
| Session |
A-3-3: Behavior Measurement and Analysis |
| Time | Thursday, 10 December, 17:30 - 19:30 |
| Presentation Time: | Thursday, 10 December, 18:00 - 18:15 Check your Time Zone |
|
All times are in New Zealand Time (UTC +13) |
| Topic |
Biomedical Signal Processing and Systems (BioSiPS): |
| Abstract |
Measuring behavior changes in humans and animals is an ongoing research in both bioscience and neuroscience, due to its applications in nerve injury recovery. Previous studies focused on sciatic nerve and its recovery process because partial damage to this nerve leads to paralyzed symptoms of entire lower body parts. They also selected the rats as model animals for experiments due to the short duration. However, their data collection and analysis processes were highly time-consuming and costly, because of visual inspection-based experiment, manual labor, and complicated equipment. To deal with this issue, DeepLabCut provides easy methods for observing and recording animal behavior in diverse settings through video data. In this study, to examine the behavioral changes in rats after sciatic nerve ligation, we (i) recorded videos of 9 rats during the first and fifth day after surgery, (ii) used DeepLabCut to track the rat's positions throughout the videos, and (iii) calculated behavior indexes based on spatio-temporal patterns that measure the behavioral changes in rats. The results in this study confirm our assumption that the rat's behavior has significant changes in the experiment as indicated by the indexes. These findings motivate us to investigate physiological processes accompanied by the recovery, and implement real-time monitoring and analysis for measuring behavior changes in rats. |